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A pharmaceutical company's pilot study (40 patients per group) detected a mean hospital stay reduction of 2 days (SD = 4 days) from a new drug. For the full trial, the company wants 80% power to detect a clinically meaningful effect of days at . How will the required sample size in the full trial compare to the pilot?
A pharmaceutical company's pilot study (40 patients per group) detected a mean hospital stay reduction of 2 days (SD = 4 days) from a new drug. For the full trial, the company wants 80% power to detect a clinically meaningful effect of days at . How will the required sample size in the full trial compare to the pilot?